Weeks of August 16, 23 and 30, 1998
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Show Number Air Week Title Program Description
SHOW #212
August 16, 1998 Liver Tumor Thermal Ablation Liver cancer is one of the deadliest cancers, and often the prognosis is very poor. Surgical removal of liver tumors is the most effective treatment, but for a variety of reasons some patients aren't good candidates for that procedure. Now, researchers are investigating another approach called thermal ablation. In this procedure, a needle is inserted through the skin directly into the tumor. Radio frequency energy is transmitted through the needle to the tip, causing it to heat the surrounding tissue, killing it. Thermal ablation is an outpatient procedure, and can be repeated as often as necessary. CONTACTS: Myong Covert, Public Affairs, University of Texas Health Science Center at San Antonio, (210)567-2570, Department of Radiology Clinical Research Coordinator: Linda Vandervelden, RN, BS, (210)567-5604; American Cancer Society, (800)ACS-2345, website: www.cancer.org
    EVERYDAY BREAKTHROUGHS: Fibronectin Preterm delivery is one of the leading causes of infant mortality in the US, but it is difficult to diagnose and can be difficult to treat. Now, investigators have discovered a marker that can signal an increased risk for preterm delivery. It's called fetal fibronectin. Fibronectin is a substance found in high concentrations between the placenta and the lining of a pregnant woman's uterus. If the placenta is starting to separate from the uterine wall, the substance will be found in the cervix and vagina. Presence of fibronectin can be an indicator of labor within 7 to 14 days. If a woman tests positive, doctors can begin aggressive treatments and activity modification in an effort to postpone labor, giving the baby more of a chance to develop. CONTACTS: Nancy Kochuk, UNC Hospitals Marketing & Public Affairs, (919)966-6046; Greg Raybuck, Matria Healthcare, Inc., (800)456-4060; Adeza Biomedical Corp., (888)PRE-TERM, website: www.adeza.com; American College of Obstetrics & Gynecology, website: www.acog.com; Interactive Pregnancy Calendar, website: www.olen.com/baby/
    Tubal Ligation Reversal/Falloposcope Tubal ligation is a form of sterilization typically considered to be permanent. But now, utilizing the latest in microsurgical techniques and specialized instruments, a doctor in North Carolina is having success reversing tubal ligations, often leading to pregnancies. The procedure is performed on an outpatient basis, and can usually expect to resume normal activities within a week. The falloposcope is a new diagnostic tool for evaluating a woman's fallopian tubes. Fallopian tube abnormalities reportedly account for 30 to 50% of female infertility. The falloposcope allows the physician to directly visualize the interior of the fallopian tubes with a real time, high resolution video image. CONTACTS: Chapel Hill Fertility Center, Gary S. Berger, MD, Julia Smith, RN, (919)968-4656, websites: www.citysearch.com/rdu/chfertilityctr, www.inciid.org/berger.html; InterNational Council on Infertility Information Dissemination, (520)544-9548, website: www.inciid.org
    Questionable Medical Devices Another in our continuing series of visits to the Museum of Questionable Medical Devices in Minneapolis, curated by collector and enthusiast Bob McCoy. We occasionally feature McCoy showing us some of the more unusual and interesting pieces in his renowned collection. CONTACT: Bob McCoy, (612)379-4046, website: www.mtn.org/~quack/
SHOW #213
August 23, 1998 Lung Volume Reduction (Emphysema) In patients with emphysema, the alveoli or air sacs in the lungs break down, causing the lungs to lose their elasticity and over-inflate, making breathing progressively more difficult. Treatment options are relatively few - drugs and exercise can help, and in some cases lung transplant is indicated, but of course that procedure is risky, and donor lungs are scarce. Now, an operation called lung volume reduction can offer another alternative. In this surgery, damaged parts of the lungs are removed, reducing volume by 20-30%. This has the effect of returning some of the lungs' elasticity, making it easier to breathe. The operation is not a cure, but can provide significant relief. A major study is now underway to assess the procedure's long-term value. CONTACTS: Joni Westerhouse, Director for Medical Communications, Washington University (St. Louis), (314)286-0120; National Emphysema Foundation, (203)852-1009, website: www.emphysemafoundation.org; American Lung Association, (800)LUNG-USA, website: www.lungusa.org
    BREAKTHROUGH PROFILES: Dr. Thomas Starzl Dr. Starzl is one of the pioneers in the field of organ transplantation. He and his team at the University of Colorado performed the world's first liver transplant in 1963. Later, he moved to the University of Pittsburgh, which under his leadership has become one of the most active and innovative centers for transplantation research and innovation. He has championed the cause of new anti-rejection drugs, such as cyclosporine in the 1970's and FK-506 in the 80's. He and his colleagues at Pittsburgh have more recently discovered the phenomenon known as chimerism, is which cells from the donated organ migrate into the recipient's body, and vice versa. This has allowed some transplant recipients to successfully wean themselves from anti-rejection medication. SEE ALSO our story on chimerism in the Program Summary for Show #127, Week of October 10, 1997. CONTACT: Lisa Rossi, News Bureau, University of Pittsburgh Medical Center, (412)647-3555
    Cartilage Transplantation (Carticel) A new procedure called Carticel has recently been approved for the repair of damaged knee cartilage. First, a sample of a patient's own healthy cartilage is extracted and sent to a facility in Massachusetts. There, the tissue is bathed in enzymes and broken down to the cellular level. Those cells are then grown and multiplied into a quantity suitable for reimplantation at the site of the knee damage. Our bodies themselves are for the most part incapable of regenerating cartilage cells. Once the reimplantation has taken place, a lengthy period of rehabilitation begins, which gives the transplant the opportunity to "take," eventually replacing the damaged cartilage and restoring functionality. CONTACTS: Kathi Ovnic, Public Affairs, Emory University Woodruff Health Sciences Center, (404)727-5686, website: www.emory.edu/WHSC/; Genzyme Corporation, Scott Gregg, (617)761-8923, website: www.genzyme.com; American Academy of Orthopedic Surgeons, website: www.aaos.org/wordhtml/pat_educ/knee2.htm
    Questionable Medical Devices Another in our continuing series of visits to the Museum of Questionable Medical Devices in Minneapolis, curated by collector and enthusiast Bob McCoy. We occasionally feature McCoy showing us some of the more unusual and interesting pieces in his renowned collection. CONTACT: Bob McCoy, (612)379-4046, website: www.mtn.org/~quack/
SHOW #214
August 30, 1998 Breast Reconstruction Recent advances in surgical techniques have improved the aesthetic and functional outcome of breast reconstruction, in which a breast is rebuilt from other tissues following a mastectomy for breast cancer. One of these, the TRAM (transverse rectus abdominus myocutaneous) flap technique is the most complex of the common procedures, but is being used more and more because results have been so dramatic. Among its advantages are that the breast can usually be given proper contour without a breast implant, donor scars that are low on the front of the body, and the fact that women with large abdomens get a "tummy tuck" as part of the procedure. Increasingly, the plastic surgeon is being included from the outset in the team of specialists who design and carry out a comprehensive treatment plan for the breast cancer patient. CONTACTS: Medical College of Virginia: Mandy Setliff, (804)828-4504, Linda Anderson, (804)828-5378, Dr. Andrea Pozez, plastic surgeon, (804)828-3037, Breast Health Center, (804)826-5116, website: www.views.vcu.edu/mcv/MasseyBreast.html; National Cancer Institute, websites: cancernet.nci.nih.gov, rex.nci.nih.gov, Cancer Information Service, (800)4-CANCER (800-422-6237); American Cancer Society, (800)ACS-2345 Breast Cancer Network website: www.cancer.org/bcn/bcn.html
    EVERYDAY BREAKTHROUGHS: Angio Advance Balloon angioplasty to clear a blockage in the coronary artery is an increasingly common procedure, and now two innovations being tested could make the patient's hospital stay shorter and more comfortable. In balloon angioplasty, a catheter is inserted into the patient's leg. Up to now, patients would have to spend days in the hospital, including 24 hours flat on their backs, to prevent bleeding at the thigh puncture site. But the two artery closing devices being tested both allow patients to stay upright during recovery, and appear to allow shorter hospital stays. CONTACT: Steve Kraushaar, Public Affairs, Washington University, (314)286-1020, website: www.wustl.edu
    Schizophrenia A new generation of drugs, known as atypical anti-psychotics, has ushered in a whole new era in the treatment of schizophrenia. Many individuals given these compounds have shown dramatic improvement, with fewer and milder side effects than the older antipsychotics. Now, Dr. Jeffrey Lieberman of the University of North Carolina, one of the world's foremost researchers on psychosis and schizophrenia, is conducting a clinical trial called the FIRST study to assess whether the atypical antipsychotics can stop the progression of schizophrenia in patients with new onset of psychosis. The theory is that early intervention and aggressive treatment, typically in the teens, when first episodes are often experienced, can improve long term outcomes for those patients. CONTACTS: Nancy Kochuk, UNC Hospitals Marketing & Public Relations, (919)966-3366, Janet Kazmer, FIRST Study, (919)966-9587; National Alliance for the Mentally Ill, (703)524-7600, website: www.nami.org; The Schizophrenia Homepage, website: www.schizophrenia.com
    BREAKTHROUGH PROFILES: M. Devin Galligan Brain cancer survivor M. Devin Galligan was diagnosed at age 24 with a malignant brain tumor. Within weeks he underwent an awake craniotomy (see Show #105), and now is undergoing chemotherapy. In November 1997, he fulfilled a lifelong dream and ran in the New York Marathon, at the same time raising money to support brain cancer research at Vanderbilt University. He has also written brochures for other adults scheduled to have neurosurgery. CONTACT: John Howser, Medical Director, Vanderbilt University Medical Center News and Public Affairs, (615)322-4747

 

 

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