Weeks of April 12, 19 and 26, 1998
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Show Number Air Week Title Program Description
SHOW #146 Week of April 12, 1998 Heart Disease/PET Scan Heart disease remains our number one killer, in spite of many strides in recent years. Now there is a pioneering physician who is convinced he has a better way to prevent and treat cardiac problems, and diagnose the extent of disease in patients without the use of invasive procedures. Dr. Lance Gould of the University of Texas - Houston has developed a comprehensive program based on his theories, and has reported some remarkable results. First of all, he relies heavily on the use of the PET (positron emission tomography) scan, a sophisticated imaging technology, to diagnose heart disease and monitor the effectiveness of therapy. He believes that PET is more accurate than current invasive diagnostic methods. Along with improved assessment, Dr. Gould's program is based on his firm belief that heart disease can be successfully prevented or reversed noninvasively, through aggressive use of cholesterol-lowering drugs and a strict low fat diet. CONTACTS: Sandra Henry, Public Affairs, UT-Houston Health Science Center, (713)500-3030, website: www.uth.tmc.edu; American Heart Association, (800)AHA-USA1, website: www.amhrt.org; American College of Cardiology, (800)253-4636, website: www.acc.org
    GENEWATCH: Salmonella Vaccine After ten years of research, scientists at Washington University have perfected an oral vaccine that protects chickens against salmonella bacteria. Using genetic engineering techniques, they have deleted two key genes in the bacterium. This weakened form of the organism is given to the fowl, and produces an immune response without making the chicks sick. It's estimated that widespread use of the vaccine could eliminate up to one fourth of the estimated four million salmonella poisoning cases in humans each year. CONTACTS: Steve Kraushaar, Washington University, (314)286-0120, website: www.wustl.edu
    Vibrant Soundbridge Up to 26 million Americans have some degree of hearing impairment. Now there is a new alternative to hearing aids for the moderate to severely hearing impaired. The Vibrant Soundbridge, consisting of both externally worn and surgically impanted components, works in the middle ear. Sound is transmitted to a tiny device in the middle ear, which vibrates, stimulating the small bones nearby. These vibrations travel to the inner ear, where they stimulate the auditory nerve and travel on to the brain to be interpreted as sound. The ear canal is left open, allowing the user to continue to experience natural sound as much as possible. The device, intended to offer sound reproduction superior to hearing aids, is now in clinical trials in the US. CONTACTS: Lori Fiber, Fischer & Partners, 310-577-7870; Symphonix Devices, Inc., (408)232-0710, website: www.symphonix.com ; House Ear Institute, (213)483-4431, website: http://www.hei.org ; American Academy of Otolaryngology - Head and Neck Surgery, (703)836-4444, website: www.entnet.org ; Better Hearing Institute, (800)EAR-WELL, website: www.betterhearing.org ; American Hearing Research Foundation, (312)726-9670
    EVERYDAY BREAKTHROUGHS: Breast Milk Breast milk is always considered to be the most nutritious food for babies, but nutritional content can vary widely from woman to woman. Now two medical students at Vanderbilt University Medical Center have devised a simple method of gauging nutritional content. It uses a standard centrifuge to measure the length of the lipid column, or creamatocrit, after it has been separated from the milk. This measurement reflects the amount of energy available in the milk. The test is practical and has the potential for widespread clinical use, particularly with premature infants in neonatal intensive care units, and babies diagnosed with failure to thrive. CONTACT: John Howser, Public Relations, Vanderbilt University Medical Center, (615)322-4747, website: www.vanderbilt.edu
SHOW #147 Week of April 19, 1998 Islet Cells Islet cells are the insulin-producing cells in the pancreas. When they become damaged or destroyed, diabetes is the result. Now, islet cells are being transplanted, and if the procedure can be perfected, it could one day lead to a cure for diabetes. Until recently, islet cell transplants were only performed in patients who were also having whole organ transplants. This was due to the fact that the transplant requires immune system suppression to prevent rejection of the foreign tissue, and the risk/benefit analysis did not justify transplanting islet cells alone. Now, clinical trials are underway at the Diabetes Research Institute at the University of Miami School of Medicine in which patients are receiving islet cells alone, but in this case in conjunction with bone marrow from the same donors, in hopes of re-educating the patient's immune system to accept the transplant, as opposed to immunosuppression. If this can be consistently and effectively accomplished, with sufficient insulin production by the transplanted islet cells, patients would eventually no longer need to take insulin. CONTACT: Mitra Zehtab, MD, Director of Medical Communications, Diabetes Research Institute, University of Miami School of Medicine, (305)243-3899, email: mzehtab@mednet.med.miami.edu, Website: drinet.med.miami.edu/drinet/cl.trials/00cl_trials_html
    BREAKTHROUGH PROFILES: Dr. Monroe Wall Dr. Wall, a chief scientist at Research Triangle Institute, Research Triangle Park, NC, was recently named recipient of the Alfred Burger Award by the American Chemical Society. He is being recognized for his discovery of two powerful anti-cancer drugs, taxol and camptothecin. The drugs were developed from the barks of two different trees. Taxol has been especially significant in fighting ovarian and breast cancer. Dr. Wall's associate, Dr. Mansukh Wani, is also featured in the story. CONTACTS: Reid Mainess, Public Relations, Research Triangle Institute, (919)541-6000, website: www.rti.org; American Chemical Society website: www.acs.org
    Wheelchairs The Human Engineering Research Lab in the School of Health and Rehabilitation Services at the University of Pittsburgh is the only wheelchair lab in the country outside of private industry. The lab tests new wheelchairs for the VA, the FDA, and large wheelchair manufacturers. They also develop new materials that are lighter and stronger, as well as new devices to increase control and mobility. CONTACT: The Pitt/VA Medical Center Human Engineering Research Lab, (412)365-4850, website: www.pitt.edu/~rstherl/index.html
    BREAKTHROUGHS IN HISTORY: Aspirin 1997 marked the one-hundredth anniversary of the synthesis of acetylsalicylic acid, the active ingredient in aspirin, by Bayer chemist Felix Hoffman. Within two years, it was on the market as a pain reliever, and by 1915, it was available without a prescription. Although other pain relievers have come along to diminish aspirin's market share, the more recently discovered cardiovascular benefits of aspirin have ensured that it will continue to play a role for a long time to come. CONTACT: Kiera Kelly, Golin/Harris Communications, (312)836-7110
SHOW #148 Week of April 26, 1998 Prosthetic Sensors A company called NovaCare-Sabolich in Oklahoma City has developed new electronic sensor systems for use in prosthetic limbs. The Sense of Feel System gives amputees the ability to feel pressure in both their upper and lower prostheses. It helps them maintain their center of gravity when walking. The Hot and Cold Sensory System contains a temperature probe in the tip of the finger of the prosthetic hand. It sends signals to electrodes attached to the residual limb, from which nerves send signals to the brain, which correctly interpret the temperature of the object. Neither of these systems are as yet available to the public. CONTACTS: Kristen Thomas or Kim Tefertiller, Public Relations, NovaCare-Sabolich Prosthetics, (405)525-4000; Patient Services Department, (800)522-4428, email: NovaCare@oandp.com, website: www.novacaresabolich.com; Limbs For Life (service organization), (888)235-5462
    BREAKTHROUGH PROFILES: Dr. Maclyn McCarty In 1944, Dr. McCarty and his colleagues at The Rockefeller University Hospital published a paper that showed that DNA is the carrier of hereditary information. Previously, it had been assumed that protein was the genetic material. Dr. McCarty's discovery laid the groundwork for Watson and Crick's subsequent discovery of the double-helix structure of DNA. CONTACT: The Rockefeller University, Office of Public Affairs, (212)327-8967
    Ulnar-Mammary Syndrome Researchers have identified genetic mutations responsible for a rare birth disorder called ulnar-mammary syndrome, which is characterized by abnormal limb, breast, and genital developments. Although the condition is extemely rare, the discovery of this genetic information could lead to important increased understanding of how normal limbs develop, what triggers the onset of puberty, and other vital functions of this particular group of genes responsible for some aspects of embryonic development. CONTACTS: Dorothy Dart, Director for Communications, University of Utah, (801)585-3470; Researchers would like to hear from families who have two or more members who have experienced birth defects in hands or fingers - email: disease @genetics.utah.edu, telephone: Dr. Michael Bamshad, Eccles Institute of Human Genetics, (801)585-3384, Dr. Peter Armstrong, Shriners Hospital for Children, (801)536-3500; For more information on ulnar-mammary syndrome and other birth defects - National Organization for Rare Disorders, Inc. (NORD), (203)746-6518 or (800)999-6673, email: orphan@nord-rdb.com, website: www.nord-rdb.com/~orphan; NIH/National Institute of Child Health and Human Development, (301)496-5133, website: www.nih.gov/nichd; NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases, (301)496-8188, website: www.nih.gov/niams; NIH Office of Rare Diseases, website: rarediseases.info.nih.gov/ord; Association of Families & Friends of Children with Limb Disorders, (716)762-9997; Association of Children's Prosthetic/Orthotic Clinics, (708)698-1694; International Center for Skeletal Dysplasia, (301)337-1250; Superkids, Inc. (newsletter for families and friends of children with limb differences), 60 Clyde St., Newton, MA 02160; For information on genetics and genetic counseling referrals - Alliance of Genetic Support Groups, (301)652-5553, email: alliance@capaccess.org, website: resourcecenter@modimes.org, website: www.modimes.org
    FUTUREX: VR Surgery Workbench Researchers have developed a high-tech training and planning tool for virtual surgical simulation. The system allows doctors to plan and practice difficult procedures before performing them on a real patient. Wearing stereoscopic glasses, the surgeon sees 3D textured models of the patient's body on the workbench display. With special controllers, they can interact with the model and simulate surgical procedures. CONTACT: Judy Kaneko, Broadcast PR Specialist, Silicon Graphics, (415)933-6171, email: jkaneko@corp.sgi.com, website: www.sgi.com

 

 

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